Quality of Life and Psychological Impacts in Patients with Hypertrophic Cardiomyopathy: A Multidisciplinary Approach
Abstract
Despite advancements in the diagnosis and management of hypertrophic cardiomyopathy (HCM), the psychosocial impact of the disease on patients' quality of life remains an underexplored area. This paper investigates the psychological and lifestyle challenges faced by individuals with HCM, focusing on the effects of physical limitations, symptom burden, and anxiety related to sudden cardiac death. Using a multidisciplinary approach, the study examines how interventions such as counseling, lifestyle modifications, and cardiac rehabilitation programs can improve mental health outcomes and overall quality of life. This research emphasizes the need for holistic care models that address both the physical and emotional aspects of HCM, promoting patient-centered management and long-term well-being.
References
Huxley, A. F. (1957). Muscle structure and theories of contraction. Progress in Biophysics and Biophysical Chemistry, 7, 255-318.
Jones, D. A., & Rutherford, O. M. (1987). Human muscle strength training: The effects of three different regimens and the nature of the resultant changes. Journal of Physiology, 391(1), 1-11. https://doi.org/10.1113/jphysiol.1987.sp016717
Kawakami, Y., Ichinose, Y., & Fukunaga, T. (1998). Architectural and functional features of human triceps surae muscles during contraction. Journal of Applied Physiology, 85(2), 398-404. https://doi.org/10.1152/jappl.1998.85.2.398
Kubo, K., Kanehisa, H., & Fukunaga, T. (2002). Effects of resistance and stretching training programs on the viscoelastic properties of human tendon structures in vivo. Journal of Applied Physiology, 92(2), 595-601. https://doi.org/10.1152/japplphysiol.00658.2001
McArdle, W. D., Katch, F. I., & Katch, V. L. (2010). Exercise Physiology: Nutrition, Energy, and Human Performance (7th ed.). Lippincott Williams & Wilkins.
Muthu, P., Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I., Gryczynski, Z., ... & Borejdo, J. (2010). Single molecule kinetics in the familial hypertrophic cardiomyopathy D166V mutant mouse heart. Journal of molecular and cellular cardiology, 48(5), 989-998.
Krupa, A., Fudala, R., Stankowska, D., Loyd, T., Allen, T. C., Matthay, M. A., ... & Kurdowska, A. K. (2009). Anti-chemokine autoantibody: chemokine immune complexes activate endothelial cells via IgG receptors. American journal of respiratory cell and molecular biology, 41(2), 155-169.
Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I., Gryczynski, Z., Zhao, J., ... & Borejdo, J. (2011). Cross-bridge kinetics in myofibrils containing familial hypertrophic cardiomyopathy R58Q mutation in the regulatory light chain of myosin. Journal of theoretical biology, 284(1), 71-81.
Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I., Gryczynski, Z., & Borejdo, J. (2010). Kinetics of a single cross-bridge in familial hypertrophic cardiomyopathy heart muscle measured by reverse Kretschmann fluorescence. Journal of Biomedical Optics, 15(1), 017011-017011.
Mettikolla, P., Luchowski, R., Gryczynski, I., Gryczynski, Z., Szczesna-Cordary, D., & Borejdo, J. (2009). Fluorescence lifetime of actin in the familial hypertrophic cardiomyopathy transgenic heart. Biochemistry, 48(6), 1264-1271.
Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I., Gryczynski, Z., & Borejdo, J. (2010). Observing cycling of a few cross‐bridges during isometric contraction of skeletal muscle. Cytoskeleton, 67(6), 400-411.
Muthu, P., Mettikolla, P., Calander, N., & Luchowski, R. 458 Gryczynski Z, Szczesna-Cordary D, and Borejdo J. Single molecule kinetics in, 459, 989-998.
Borejdo, J., Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I., & Gryczynski, Z. (2021). Surface plasmon assisted microscopy: Reverse kretschmann fluorescence analysis of kinetics of hypertrophic cardiomyopathy heart.
Mettikolla, Y. V. P. (2010). Single molecule kinetics in familial hypertrophic cardiomyopathy transgenic heart. University of North Texas Health Science Center at Fort Worth.
Mettikolla, P., Luchowski, R., Chen, S., Gryczynski, Z., Gryczynski, I., Szczesna-Cordary, D., & Borejdo, J. (2010). Single Molecule Kinetics in the Familial Hypertrophic Cardiomyopathy RLC-R58Q Mutant Mouse Heart. Biophysical Journal, 98(3), 715a.